CorNeat eShunt 

A revolutionary solution for those who suffer from glaucoma

About Glaucoma 

Glaucoma is a disease of the eye's optic nerve that impacts the lives of about 80 million people globally. Damage to the optic nerve takes place when fluid pressure builds up in the front of the eye (the anterior chamber). Excess fluid, called the aqueous humor, increases the eye's intraocular pressure which in turn damages the optic nerve. This damage leads to partial yet gradual loss of the visual field, usually starting from the periphery but eventually leading to the loss of central vision and blindness.


Current treatment modalities aim to control intraocular pressure by either reducing the aqueous humor production or increasing its drainage/absorption. These include drops, laser surgery, MIGS (Minimally Invasive Glaucoma Shunts), incisional surgery and glaucoma drainage devices. All these treatment options lose their effectiveness within a limited timeframe.  


CorNeat eShunt Advantages 


The outlet of the eShunt is placed in the intraconal space, a space with minimal fibrotic potential


Scarring is the major cause of failure of any surgical approach to glaucoma and until the arrival of the eShunt no attempt has been made to drain the excess fluid to this deep orbital space


Covered with a synthetic, non-degradable, ECM-like material that stimulates cellular growth - integrating the tube into the subconjunctival space


Eliminates the need for using a tissue patch


Shortens the procedure and secures the device to the eye wall permanently  

Ease of Implantation 

Implantation procedure can be completed in under 15 minutes


Does not require additional, processed, tissue


Will probably not require an introducer or a dedicated tool

Physiological Approach

Engineered to imitate our own, physiologic, drainage pathways


Reacts to the changes in intraocular pressure and drains only the amount needed

CorNeat eShunt 

The CorNeat eShunt is determined to revolutionize the treatment of glaucoma. It is designed to regulate the intraocular pressure and addresses the shortcomings of existing solutions. Using advanced materials, the CorNeat eShunt inlet, which is placed in the anterior chamber angle, mimics the trabecular meshwork’s function in terms of flow resistance. The CorNeat eShunt outlet is uniquely positioned in the intraconal space, an area that does not scar and clog and can absorb the drained aqueous humor. The CorNeat eShunt tube, which is covered by a synthetic ECM layer, seamlessly integrates with the ocular tissue as it traverses the subconjunctival space, significantly shortening the surgical procedure.

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Regulatory Path 

The CorNeat eShunt has successfully passed initial bench tests and animal trials demonstrating seamless integration and the ability to reduce and regulate intraocular pressure. The R&D and preclinical phases are expected to take 12-15 months.


CorNeat eShunt device marketing is pending regulatory approvals. 


How is glaucoma diagnosed?

There are three factors involved in the definition of glaucoma: (i) Intra Ocular Pressure (IOP), (ii) specific and pathognomonic damage to the optic nerve, (iii) visual field defects. When diagnosing glaucoma at least two of these three factors need to be in alignment with the diagnosis of glaucoma.

Who is at risk of developing glaucoma?

Glaucoma is a disease of the elderly meaning that the older you are the higher your chances are of developing glaucoma. Genetic factors also play a key role in determining the risk of developing glaucoma as well as having connective tissue, inflammatory and vascular diseases.

What is “normal” eye pressure?

There is no right answer to this question as normal pressure is a personal trait. Damage incurred to the optic nerve in glaucoma results from a more complex calculation, one that takes into account the impact of one’s intra-ocular (eye) pressure, intra-cerebral (brain) pressure and the difference between them. Some of the patients continue to progress even though they seem stabilized in terms of pressure while others have stable visual fields regardless of pressure measurements higher than the normal limit. Personalized care is at the basis of glaucoma management.

Is there a cure for glaucoma?

Currently no, but there are treatment options that attempt to preserve vision with varying degrees of success. Treatment modalities vary from eye drops, laser applications and surgical procedures.

Are there different kinds of glaucoma?

Yes; Primary Open Angle Glaucoma (POAG), Acute and Chronic Angle Closure Glaucoma, Normal Tension Glaucoma, Secondary Glaucomas resulting from other disease processes, Congenital and Juvenile Glaucomas.


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